Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 12/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185060 | 0.92 | SMN1; SMN2 (0.47) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL31184359 | 0.92 | POLB (0.47) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL31185080 | 0.88 | MALT1 (0.53) | MALT1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31184508 | 0.88 | ALDH1A1 (0.45) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL31184841 | 0.87 | POLB (0.45) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL31184671 | 0.86 | MALT1 (0.58) | MALT1SMN1; SMN2 | |
| SCHEMBL31184793 | 0.86 | ALDH1A1 (0.42) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL31184756 | 0.85 | POLB (0.43) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL31184709 | 0.84 | MALT1 (0.51) | MALT1SMN1; SMN2MAPT | |
| SCHEMBL31184644 | 0.84 | MAPT (0.43) | MALT1SMN1; SMN2ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |