Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184672 | 0.92 | MAPT (0.36) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31184478 | 0.92 | MAPT (0.38) | ALDH1A1MAPTRECQLKMT2AMEN1 | |
| SCHEMBL31184867 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL31184579 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTRECQLHPGDKMT2A | |
| SCHEMBL31184603 | 0.86 | MALT1 (0.52) | ALDH1A1MAPTHPGDMALT1SMN1; SMN2 | |
| SCHEMBL31184987 | 0.83 | HTR2B (0.36) | MAPTTP53 | |
| SCHEMBL31184984 | 0.80 | HTR2A (0.38) | MAPTKMT2AMEN1LMNATP53 | |
| SCHEMBL31184643 | 0.80 | PARP1 (0.37) | MAPTKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL31185021 | 0.80 | MAPT (0.36) | ALDH1A1MAPTRECQLKMT2AMEN1 | |
| SCHEMBL31184638 | 0.80 | PARP1 (0.37) | MAPTKMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |