Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 16/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.44 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184671 | 0.88 | MALT1 (0.58) | MALT1SMN1; SMN2 | |
| SCHEMBL31184603 | 0.84 | MALT1 (0.52) | MALT1SMN1; SMN2MAPT | |
| SCHEMBL31185080 | 0.83 | MALT1 (0.53) | MALT1SMN1; SMN2 | |
| SCHEMBL31184938 | 0.80 | MALT1 (0.47) | MALT1SMN1; SMN2CHKACHKB | |
| SCHEMBL31185032 | 0.80 | MALT1 (0.44) | MALT1SMN1; SMN2MAPT | |
| SCHEMBL31184878 | 0.79 | MALT1 (0.45) | MALT1SMN1; SMN2MAPTCHKACHKB | |
| SCHEMBL31184899 | 0.78 | MALT1 (0.45) | MALT1SMN1; SMN2CHKACHKB | |
| SCHEMBL31184902 | 0.78 | MALT1 (0.54) | MALT1SMN1; SMN2 | |
| SCHEMBL31184359 | 0.76 | POLB (0.47) | MALT1SMN1; SMN2MAPTCHKACHKB | |
| SCHEMBL31185060 | 0.76 | SMN1; SMN2 (0.47) | MALT1SMN1; SMN2MAPTCHKACHKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |