Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509012 | 0.86 | POLB (0.50) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL31184543 | 0.86 | POLB (0.50) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL28509010 | 0.86 | POLB (0.50) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL29619023 | 0.85 | POLB (0.64) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL31184825 | 0.85 | ALDH1A1 (0.52) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL31184662 | 0.81 | POLB (0.47) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL31185020 | 0.81 | POLB (0.47) | POLBSMN1; SMN2LMNAHTTHPGD | |
| SCHEMBL31679547 | 0.80 | ALDH1A1 (0.56) | POLBSMN1; SMN2LMNAMEN1ALOX12 | |
| SCHEMBL8708428 | 0.80 | ALDH1A1 (0.56) | POLBSMN1; SMN2LMNAMEN1ALOX12 | |
| SCHEMBL6154728 | 0.77 | PTPN2 (0.49) | LMNAHPGDMEN1KMT2APTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |