Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 12/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184418 | 0.94 | ALDH1A1 (0.39) | MALT1SMN1; SMN2ACHEALDH1A1HPGD | |
| SCHEMBL31184593 | 0.92 | ALDH1A1 (0.39) | SMN1; SMN2ACHEALDH1A1HPGD | |
| SCHEMBL31184917 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2ACHEMAPTALDH1A1HPGD | |
| SCHEMBL31184767 | 0.88 | MALT1 (0.45) | MALT1SMN1; SMN2ACHEMAPTALDH1A1 | |
| SCHEMBL31185080 | 0.83 | MALT1 (0.53) | MALT1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31184614 | 0.82 | ALDH1A1 (0.40) | MALT1SMN1; SMN2ACHEMAPTALDH1A1 | |
| SCHEMBL31184945 | 0.81 | MCHR1 (0.38) | SMN1; SMN2ACHEALDH1A1HPGD | |
| SCHEMBL31184541 | 0.81 | JAK2 (0.38) | — | |
| SCHEMBL31184709 | 0.80 | MALT1 (0.51) | MALT1SMN1; SMN2MAPT | |
| SCHEMBL31184603 | 0.79 | MALT1 (0.52) | MALT1SMN1; SMN2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |