Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185055 | 0.80 | ALDH1A1 (0.46) | NPSR1MEN1KMT2ARAB9AAAK1 | |
| SCHEMBL6639904 | 0.75 | SMN1; SMN2 (0.46) | NPSR1MEN1KMT2AAAK1EPHX2 | |
| SCHEMBL6639898 | 0.75 | SMN1; SMN2 (0.46) | NPSR1MEN1KMT2AAAK1EPHX2 | |
| SCHEMBL31184635 | 0.75 | POLB (0.53) | GRM4LMNAALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL6639136 | 0.75 | SMN1; SMN2 (0.46) | NPSR1MEN1KMT2AAAK1EPHX2 | |
| SCHEMBL6639133 | 0.75 | SMN1; SMN2 (0.46) | NPSR1MEN1KMT2AAAK1EPHX2 | |
| SCHEMBL31184396 | 0.75 | POLB (0.53) | GRM4LMNAALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL6639139 | 0.75 | SMN1; SMN2 (0.46) | NPSR1MEN1KMT2AAAK1EPHX2 | |
| SCHEMBL31184530 | 0.74 | POLB (0.58) | MEN1KMT2AGRM4ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL31185115 | 0.74 | POLB (0.52) | GRM4LMNAALDH1A1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |