Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CHKA | P35790 | 3/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184972 | 0.88 | POLB (0.44) | MTNR1AMTNR1BKMT2ATSHRALDH1A1 | |
| SCHEMBL31184640 | 0.88 | POLB (0.45) | KMT2ATSHRALDH1A1CHKACHKB | |
| SCHEMBL31184475 | 0.88 | POLB (0.49) | KMT2AMEN1TP53ALDH1A1CHKA | |
| SCHEMBL31184979 | 0.86 | ALDH1A1 (0.46) | KMT2AMEN1KDM4ETSHRALDH1A1 | |
| SCHEMBL31184761 | 0.86 | MAPT (0.43) | MTNR1AMTNR1BKMT2AMEN1TSHR | |
| SCHEMBL31184809 | 0.85 | MAPK1 (0.42) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL31184468 | 0.85 | TP53 (0.44) | KMT2ATP53TSHRALDH1A1IDO1 | |
| SCHEMBL31184673 | 0.85 | MALT1 (0.43) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL31184499 | 0.85 | MALT1 (0.46) | KMT2AMEN1ALDH1A1CHKACHKB | |
| SCHEMBL31185049 | 0.84 | ALDH1A1 (0.44) | KMT2AKDM4ETSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |