Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185020 | 0.82 | POLB (0.47) | SMN1; SMN2RAB9ANPC1CYP1A2HPGD | |
| SCHEMBL31184662 | 0.82 | POLB (0.47) | SMN1; SMN2RAB9ANPC1CYP1A2HPGD | |
| SCHEMBL31184474 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2RAB9ANPC1HPGDHTT | |
| SCHEMBL31185017 | 0.78 | POLB (0.56) | SMN1; SMN2CYP1A2HPGDCYP2C19GAA | |
| SCHEMBL31184543 | 0.76 | POLB (0.50) | SMN1; SMN2RAB9ANPC1CYP1A2HPGD | |
| SCHEMBL28509012 | 0.76 | POLB (0.50) | SMN1; SMN2RAB9ANPC1CYP1A2HPGD | |
| SCHEMBL28509010 | 0.76 | POLB (0.50) | SMN1; SMN2RAB9ANPC1CYP1A2HPGD | |
| SCHEMBL31184928 | 0.76 | POLB (0.57) | SMN1; SMN2CYP1A2HPGDCYP2C19MEN1 | |
| SCHEMBL31184635 | 0.75 | POLB (0.53) | SMN1; SMN2CYP1A2HPGDCYP2C19GAA | |
| SCHEMBL31184396 | 0.75 | POLB (0.53) | SMN1; SMN2CYP1A2HPGDCYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |