Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184983 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184879 | 0.87 | CHKA (0.42) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184462 | 0.87 | CYP3A4 (0.40) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184693 | 0.86 | MALT1 (0.45) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184519 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184510 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184993 | 0.82 | CHKA (0.37) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184573 | 0.79 | MALT1 (0.46) | SMN1; SMN2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184952 | 0.77 | CHKA (0.37) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 | |
| SCHEMBL31184831 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1LMNAHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |