Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184878 | 0.88 | MALT1 (0.45) | CHKAALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL31184938 | 0.88 | MALT1 (0.47) | CHKAALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL31184671 | 0.86 | MALT1 (0.58) | SMN1; SMN2 | |
| SCHEMBL31185035 | 0.75 | MALT1 (0.43) | CHKAALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL31184709 | 0.74 | MALT1 (0.51) | CHKASMN1; SMN2MAPT | |
| SCHEMBL31184841 | 0.74 | POLB (0.45) | CHKAALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL31185060 | 0.73 | SMN1; SMN2 (0.47) | CHKAALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL31184359 | 0.73 | POLB (0.47) | CHKAALDH1A1HTTSMN1; SMN2LMNA | |
| SCHEMBL8324607 | 0.72 | MTNR1A (0.71) | ALDH1A1HTTSMN1; SMN2HPGDNPSR1 | |
| SCHEMBL31185102 | 0.72 | POLB (0.44) | CHKAALDH1A1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |