Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 4/20 | 0.40 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184628 | 0.90 | CHRM4 (0.42) | NAMPTCHRM4CHRM1ALDH1A1CYP1A2 | |
| SCHEMBL31184791 | 0.85 | ACHE (0.44) | CHRM4CHRM1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31184662 | 0.82 | POLB (0.47) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL31185020 | 0.82 | POLB (0.47) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL28509012 | 0.78 | POLB (0.50) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL28509010 | 0.78 | POLB (0.50) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL31184543 | 0.78 | POLB (0.50) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL31184666 | 0.76 | HTT (0.39) | EPHX2ALDH1A1CYP1A2CYP3A4MAPK1 | |
| SCHEMBL31184505 | 0.75 | POLB (0.39) | ALDH1A1CYP1A2CYP3A4MAPK1CYP2C19 | |
| SCHEMBL31184732 | 0.75 | CALCRL (0.49) | CALCRLRAMP1NAMPTCHRM4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |