Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 15/20 | 0.49 |
| ▸ | RAMP1 | O60894 | 12/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CALCA | P06881 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184791 | 0.86 | ACHE (0.44) | MAPTCHRM4 | |
| SCHEMBL31184628 | 0.83 | CHRM4 (0.42) | MAPTCHRM4NAMPT | |
| SCHEMBL11127305 | 0.76 | ALDH1A1 (0.55) | CALCRLRAMP1L3MBTL1 | |
| SCHEMBL22869715 | 0.76 | HSD11B1 (0.73) | CHRM4 | |
| SCHEMBL30231295 | 0.75 | CALCRL (0.58) | CALCRLRAMP1CHRM4CALCA | |
| SCHEMBL31184754 | 0.75 | MAPT (0.47) | MAPTL3MBTL1 | |
| SCHEMBL31184406 | 0.74 | POLB (0.43) | MAPT | |
| SCHEMBL31184884 | 0.74 | POLB (0.43) | — | |
| SCHEMBL31184899 | 0.74 | MALT1 (0.45) | L3MBTL1 | |
| SCHEMBL22869654 | 0.73 | HSD11B1 (0.66) | CALCRLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |