Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8925933 | 0.84 | ALOX5 (0.60) | ALOX5MAPTPPARGKMT2AMEN1 | |
| SCHEMBL7091491 | 0.83 | GAA (0.69) | ALOX5MAPTPPARGKMT2AMEN1 | |
| SCHEMBL11179642 | 0.81 | ALOX5 (0.68) | ALOX5MAPTPPARGKMT2AMEN1 | |
| SCHEMBL7091499 | 0.80 | ALOX5 (0.58) | ALOX5MAPTKMT2AMEN1GAA | |
| SCHEMBL7086047 | 0.80 | MAPT (0.73) | ALOX5MAPTKMT2AMEN1GAA | |
| SCHEMBL22076399 | 0.80 | RAB9A (0.57) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL30062014 | 0.79 | ALDH1A1 (0.59) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL194989 | 0.79 | ALDH1A1 (0.59) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL27529813 | 0.79 | ALOX5 (0.57) | ALOX5MAPTPPARGKMT2AMEN1 | |
| SCHEMBL8741183 | 0.79 | ALOX5 (0.53) | ALOX5MAPTPPARGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024192321-A2 | SULFINE-BASED COMPOUNDS FOR GENERATING HYDROGEN PERSULFIDE | BROWN UNIVERSITY (US) | 2024-09-19 | — | — | WO | disclosed |