Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 9/20 | 0.45 |
| ▸ | GRM5 | P41594 | 8/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31189189 | 0.88 | KIT (0.47) | KITGRM1GRM5CYP11B2PDK4 | |
| SCHEMBL15504614 | 0.80 | KIT (0.59) | KITCNR1GRM1GRM5CYP11B2 | |
| SCHEMBL29138576 | 0.79 | GRM1 (0.53) | CNR1GRM1GRM5CYP11B2PDK4 | |
| SCHEMBL30366133 | 0.79 | GRM1 (0.49) | CNR1GRM1GRM5CYP11B2PDK4 | |
| SCHEMBL30899649 | 0.79 | GRM1 (0.49) | CNR1GRM1GRM5CYP11B2PDK4 | |
| SCHEMBL25457026 | 0.79 | CNR1 (0.49) | KITCNR1GRM1GRM5PDK4 | |
| SCHEMBL31583898 | 0.78 | GRM1 (0.55) | CNR1GRM1GRM5CYP11B2PDK4 | |
| SCHEMBL74150 | 0.78 | TNK2 (0.49) | CNR1GRM1GRM5CYP11B2PDK4 | |
| SCHEMBL7970682 | 0.78 | CNR1 (0.49) | CNR1GRM1GRM5PDK4PDE10A | |
| SCHEMBL31189168 | 0.77 | KIT (0.43) | KITGRM1GRM5CYP11B2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698541-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024218207-A1 | THIENO[3,2-B]PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-24 | — | — | WO | disclosed |