Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.46 |
| ▸ | GRM5 | P41594 | 9/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | ATR | Q13535 | 2/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366133 | 0.88 | GRM1 (0.49) | TNK2CYP11B2CNR1GRM1GRM5 | |
| SCHEMBL30899649 | 0.88 | GRM1 (0.49) | TNK2CYP11B2CNR1GRM1GRM5 | |
| SCHEMBL21512721 | 0.87 | TNK2 (0.49) | TNK2CYP11B2GRM1GRM5PDK4 | |
| SCHEMBL29968677 | 0.87 | TNK2 (0.49) | TNK2CYP11B2GRM1GRM5PDK4 | |
| SCHEMBL1463273 | 0.87 | GRM1 (0.51) | TNK2CYP11B2GRM1GRM5PDK4 | |
| SCHEMBL31583898 | 0.87 | GRM1 (0.55) | TNK2CYP11B2CNR1GRM1GRM5 | |
| SCHEMBL25311684 | 0.83 | GRM1 (0.48) | TNK2CYP11B2CNR1GRM1GRM5 | |
| SCHEMBL31083549 | 0.83 | GRM1 (0.48) | TNK2CYP11B2CNR1GRM1GRM5 | |
| SCHEMBL27929255 | 0.83 | TRPV1 (0.41) | — | |
| SCHEMBL29138576 | 0.82 | GRM1 (0.53) | TNK2CYP11B2CNR1GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045422-B2 | Piperidine derivatives with pesticidal properties | SYNGENTA PARTICIPATIONS AG (CH) | 2015-06-02 | — | — | US | disclosed |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-21 | — | — | US | disclosed |
| US-8546569-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| EP-1763302-B1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-20120270885-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-10-25 | — | — | US | disclosed |
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090042938-A1 | Chemical Compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120270885-A1 | CHEMICAL COMPOUNDS | H1-0, CHRM1, MRM1 | TNK2 2371/4885CYP11B2 1232/4885CNR1 303/4885 |
| US-20090042938-A1 | Chemical Compounds | CHRM1, MRM1, H1-0 | TNK2 2714/4885CYP11B2 1304/4885CNR1 277/4885 |
| US-20130310399-A1 | CHEMICAL COMPOUNDS | ACHE, CHRM1, CHRM2 | TNK2 2923/4885CYP11B2 2653/4885CNR1 427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.