Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31586483 | 0.81 | GAA (0.38) | PIM1PIM2NPC1ALDH1A1RAB9A | |
| SCHEMBL3402451 | 0.81 | GAA (0.44) | PIM1PIM2ALDH1A1MAP2K4ADRA2A | |
| SCHEMBL15740705 | 0.78 | PIM1 (0.33) | PIM1PIM2NPC1ALDH1A1RAB9A | |
| SCHEMBL31190818 | 0.77 | PIM1 (0.35) | PIM1PIM2MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL19616582 | 0.76 | MAPK8 (0.30) | NPC1RAB9A | |
| SCHEMBL30540792 | 0.74 | RAB9A (0.42) | PIM1PIM2NPC1ALDH1A1RAB9A | |
| SCHEMBL15742197 | 0.72 | PIM1 (0.33) | PIM1PIM2 | |
| SCHEMBL19616876 | 0.71 | PRKAB2 (0.32) | — | |
| SCHEMBL19616623 | 0.71 | MAPK8 (0.33) | — | |
| SCHEMBL19616539 | 0.71 | CHUK (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |