Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4925533 | 1.00 | HPGD (0.64) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4922166 | 1.00 | HPGD (0.64) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4922178 | 1.00 | HPGD (0.64) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6162353 | 0.94 | HPGD (0.57) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6162246 | 0.94 | HPGD (0.57) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6442016 | 0.87 | HPGD (0.51) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6159065 | 0.87 | HPGD (0.50) | HPGDTSHRDPP4SMN1; SMN2HTT | |
| SCHEMBL6161961 | 0.87 | HPGD (0.50) | HPGDTSHRSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6158312 | 0.87 | HPGD (0.50) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6157539 | 0.87 | HPGD (0.50) | HPGDTSHRDPP4SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |