Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190825 | 1.00 | HPGD (0.64) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4925533 | 1.00 | HPGD (0.64) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4922166 | 1.00 | HPGD (0.64) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6162353 | 0.94 | HPGD (0.57) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6162246 | 0.94 | HPGD (0.57) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6442016 | 0.87 | HPGD (0.51) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6159065 | 0.87 | HPGD (0.50) | HPGDTSHRDPP4SMN1; SMN2HTT | |
| SCHEMBL6161961 | 0.87 | HPGD (0.50) | HPGDTSHRSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6158312 | 0.87 | HPGD (0.50) | HPGDTSHRDPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL6157539 | 0.87 | HPGD (0.50) | HPGDTSHRDPP4SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724084-B | Synthesis method of (S) -3-hydroxy-1-benzylpyrrolidine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-110724084-A | Synthesis method of (S) -3-hydroxy-1-benzylpyrrolidine | 苏州永健生物医药有限公司 | 2020-01-24 | — | — | CN | claimed |
| CN-109929327-A | Inorganic nano material prints ink and its preparation method and application | TCL集团股份有限公司 | 2019-06-25 | — | — | CN | claimed |
| EP-1325146-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 4-HYDROXY-2-PYRROLIDINONE AND N-SUBSTITUTED 4-HYDROXY-2-PYRROLIDINONES BY ENZYMATIC HYDROXYLATION | EIDGENOESSICHE TECH HOCHSCHULE (CH) | 2005-12-14 | — | — | EP | claimed |
| US-20040009562-A1 | Process for preparing optically active 4-hydroxy-2-pyrrolidinone and n-substituted 4-hydroxy-2-pyrrolidinones by enzymatic hydroxylation | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2004-01-15 | — | — | US | claimed |
| EP-1325146-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE 4-HYDROXY-2-PYRROLIDINONE AND N-SUBSTITUTED 4-HYDROXY-2-PYRROLIDINONES BY ENZYMATIC HYDROXYLATION | Eidgenössiche Technische Hochschule Zürich (CH) | 2003-07-09 | — | — | EP | claimed |
| WO-2002031174-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE 4-HYDROXY-2-PYRROLIDINONE AND N-SUBSTITUTED 4-HYDROXY-2-PYRROLIDINONES BY ENZYMATIC HYDROXYLATION | EIDGENÖSSICHE TECHNISCHE HOCHSCHULE ZÜRICH (CH) | 2002-04-18 | — | — | WO | claimed |
| EP-1197561-A1 | Process for preparing optically active 4-hydroxy-2-pyrrolidinone and N-substituted 4-hydroxy-2-pyrrolidinones by enzymatic hydroxylation | Eidgenössische Technische Hochschule Zürich (CH) | 2002-04-17 | — | — | EP | claimed |
| JP-1254657-A | — | — | None | — | — | JP | disclosed |
| JP-1045360-A | — | — | None | — | — | JP | disclosed |
| JP-3200762-A | — | — | None | — | — | JP | disclosed |
| CN-110724084-B | Synthesis method of (S) -3-hydroxy-1-benzylpyrrolidine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110724084-B | Synthesis method of (S) -3-hydroxy-1-benzylpyrrolidine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| WO-2021094312-A1 | PYRROLIDINE AND BICYCLOHETEROARYL CONTAINING OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-20 | — | — | WO | disclosed |
| EP-0452143-B1 | Process for preparing optically active 3-hydroxypyrrolidine derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 1994-10-05 | — | — | EP | disclosed |
| US-5144042-A | PROCESS FOR PREPARING OPTICALLY ACTIVE 3-HYDROXYPYRROLIDINE DERIVATIVES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-09-01 | — | — | US | disclosed |
| EP-0452143-A2 | Process for preparing optically active 3-hydroxypyrrolidine derivatives | Takasago International Corporation (JP) | 1991-10-16 | — | — | EP | disclosed |
| JP-H03200762-A | PRODUCTION OF 1-BENZYL-3-PYRROLIDINOL | KANEGAFUCHI CHEM IND CO LTD | 1991-09-02 | — | — | JP | disclosed |
| JP-H01254657-A | PRODUCTION OF 1-BENZYL-3-PYRROLIDINOL | KANEGAFUCHI CHEM IND CO LTD | 1989-10-11 | — | — | JP | disclosed |
| JP-S6445360-A | 1-BENZYL-4-HYDROXY-2-PYRROLIDONE DERIVATIVE AND PRODUCTION THEREOF | DENKI KAGAKU KOGYO KK | 1989-02-17 | — | — | JP | disclosed |