Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | AKT2 | P31751 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190916 | 0.89 | NPC1 (0.43) | MAPK10AKT1AKT2NPC1RAB9A | |
| SCHEMBL18648907 | 0.85 | P2RX3 (0.50) | MAPK10P2RX3NPC1RAB9AMAPT | |
| SCHEMBL31091863 | 0.83 | MAPK10 (0.39) | MAPK10P2RX3AKT1AKT2NPC1 | |
| SCHEMBL31091950 | 0.83 | AKT1 (0.43) | MAPK10P2RX3AKT1AKT2NPC1 | |
| SCHEMBL31190910 | 0.82 | MAPK10 (0.45) | MAPK10P2RX3NPC1RAB9AP2RX2 | |
| SCHEMBL31190885 | 0.74 | DHODH (0.39) | MAPK10NPC1RAB9A | |
| SCHEMBL31190909 | 0.74 | ALDH1A1 (0.39) | MAPK10NPC1RAB9AMAPTCYP3A4 | |
| SCHEMBL18892168 | 0.74 | P2RX3 (0.43) | P2RX3NPC1RAB9AMAPTP2RX2 | |
| SCHEMBL31190888 | 0.74 | AKT1 (0.42) | MAPK10AKT1AKT2NPC1RAB9A | |
| SCHEMBL31191052 | 0.74 | DPP4 (0.34) | MAPK10NPC1RAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220543-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |