Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | AKT2 | P31751 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190932 | 0.81 | ALDH1A1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31190943 | 0.77 | RAB9A (0.45) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31091925 | 0.76 | AKT1 (0.46) | AKT1AKT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31190916 | 0.74 | NPC1 (0.43) | AKT1AKT2NPC1RAB9AMAPK10 | |
| SCHEMBL31190884 | 0.74 | MAPK10 (0.56) | AKT1AKT2NPC1RAB9AMAPK10 | |
| SCHEMBL31190927 | 0.73 | CGAS (0.40) | AKT1AKT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31190886 | 0.73 | AKT1 (0.42) | AKT1AKT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31091889 | 0.72 | AKT1 (0.41) | AKT1AKT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31091944 | 0.72 | AKT1 (0.43) | AKT1AKT2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31190889 | 0.71 | GRM2 (0.42) | AKT1AKT2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220543-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |