Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24897524 | 1.00 | KIF11 (0.53) | KIF11SYKMAPK14MAPTKDM4E | |
| SCHEMBL30832785 | 0.78 | BCL6 (0.51) | MAPK14MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL20773220 | 0.78 | BCL6 (0.51) | MAPK14MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL24897475 | 0.73 | SYK (0.50) | SYKMAPK14MAPTKDM4ETP53 | |
| SCHEMBL10338441 | 0.72 | PDE3B (0.60) | KIF11SYKMAPTKDM4ETP53 | |
| SCHEMBL12361999 | 0.72 | PDE3B (0.54) | KIF11SYKMAPTTP53SMN1; SMN2 | |
| SCHEMBL20772989 | 0.71 | BRD4 (0.49) | MAPK14MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL30832794 | 0.71 | BRD4 (0.49) | MAPK14MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL4607773 | 0.70 | MAPT (0.86) | MAPK14MAPTKDM4ETP53SMN1; SMN2 | |
| SCHEMBL18188273 | 0.70 | MKNK1 (0.47) | KIF11SYKMAPTTP53MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4470618-A2 | HETEROCYCLIC COMPOUNDS FOR MEDICAL TREATMENT | C4 Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |