Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338289 | 0.76 | PDE3B (0.57) | PDE3BPDE3AKMT2AKDM4EMEN1 | |
| SCHEMBL12361999 | 0.75 | PDE3B (0.54) | PDE3BPDE3AKIF11SYKMKNK1 | |
| SCHEMBL16208489 | 0.73 | KIF11 (1.00) | KIF11SYKKMT2AMEN1POLB | |
| SCHEMBL24897524 | 0.72 | KIF11 (0.53) | KIF11SYKMKNK1KMT2AKDM4E | |
| SCHEMBL31191602 | 0.72 | KIF11 (0.53) | KIF11SYKMKNK1KMT2AKDM4E | |
| SCHEMBL10338403 | 0.71 | PDE3B (0.61) | PDE3BPDE3ASYKKDM4EPOLB | |
| SCHEMBL12433112 | 0.71 | PDE3B (0.59) | PDE3BPDE3A | |
| SCHEMBL18175838 | 0.70 | KIF11 (0.46) | PDE3BPDE3AKIF11SYKMKNK1 | |
| SCHEMBL14651169 | 0.69 | SYK (1.00) | SYK | |
| SCHEMBL15618645 | 0.69 | MKNK1 (0.66) | KIF11SYKMKNK1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2059578-A | — | — | None | — | — | JP | disclosed |
| JP-H0259578-A | BENZOTHIAZOLONE DERIVATIVE OR SALT THEREOF | MITSUBISHI KASEI CORP | 1990-02-28 | — | — | JP | disclosed |