Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22724808 | 1.00 | MAPT (0.61) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL334142 | 0.84 | L3MBTL1 (0.64) | MAPTMEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL3788796 | 0.81 | L3MBTL1 (0.60) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL12662131 | 0.81 | L3MBTL1 (0.60) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL9402833 | 0.81 | L3MBTL1 (0.60) | MAPTLMNAALDH1A1L3MBTL1HTT | |
| SCHEMBL1117871 | 0.81 | MAPT (0.67) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL18701612 | 0.80 | HTT (0.68) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29881333 | 0.80 | MAPT (0.56) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL6814964 | 0.80 | MAPT (0.56) | MAPTMEN1KMT2ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL28790673 | 0.79 | MAPT (0.65) | MAPTMEN1KMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924296-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-09-17 | — | — | CN | disclosed |