Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138761 | 0.91 | L3MBTL1 (0.53) | L3MBTL1EPHX1EPHX2KDRCYP3A4 | |
| SCHEMBL8410377 | 0.87 | EPHX1 (0.61) | EPHX1EPHX2CYP3A4APEX1POLB | |
| SCHEMBL11556903 | 0.87 | EPHX1 (0.61) | EPHX1EPHX2CYP3A4APEX1POLB | |
| SCHEMBL3810058 | 0.86 | MAPT (0.60) | L3MBTL1KDRNPC1MEN1KMT2A | |
| SCHEMBL15946926 | 0.86 | L3MBTL1 (0.60) | L3MBTL1KDRCA2CA9NPC1 | |
| SCHEMBL9402833 | 0.86 | L3MBTL1 (0.60) | L3MBTL1EPHX2KDRCA2CA9 | |
| SCHEMBL3788796 | 0.86 | L3MBTL1 (0.60) | L3MBTL1NPC1MEN1KMT2AMAPT | |
| SCHEMBL12662131 | 0.86 | L3MBTL1 (0.60) | L3MBTL1CA2NPC1MEN1KMT2A | |
| SCHEMBL22724808 | 0.84 | MAPT (0.61) | L3MBTL1CYP3A4CA2CA9NPC1 | |
| SCHEMBL31192562 | 0.84 | MAPT (0.61) | L3MBTL1CYP3A4CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130303621-A1 | Method For Inhibiting Osteoclast Development | WEST VIRGINIA UNIVERSITY RESEARCH CORPORATION | 2013-11-14 | — | — | US | claimed |
| US-11654123-B2 | Method for inhibiting osteoclast development | WEST VIRGINIA UNIVERSITY (US) | 2023-05-23 | — | — | US | disclosed |
| US-11136315-B2 | CXCR2 antagonist | MEDSHINE DISCOVERY INC. (CN) | 2021-10-05 | — | — | US | disclosed |
| EP-3738956-A1 | CXCR2 ANTAGONIST | Medshine Discovery Inc. (CN) | 2020-11-18 | — | — | EP | disclosed |
| US-20200352884-A1 | METHOD FOR INHIBITING OSTEOCLAST DEVELOPMENT | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2020-11-12 | — | — | US | disclosed |
| US-20200339549-A1 | CXCR2 ANTAGONIST | Shenzhen Optimum Biological Technology Co., Ltd (CN) | 2020-10-29 | — | — | US | disclosed |
| US-10682320-B2 | Method for inhibiting osteoclast development | WEST VIRGINIA UNIVERSITY (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180207145-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED | 2018-07-26 | — | — | US | disclosed |
| CN-107072976-A | Pharmaceutical composition comprising Danirixin for the treatment of infectious diseases | 葛兰素史克知识产权第二有限公司 | 2017-08-18 | — | — | CN | disclosed |
| US-20170100385-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2017-04-13 | — | — | US | disclosed |
| US-4093446-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-06-06 | — | — | US | disclosed |
| US-4083713-A | CONTROLLING WEEDS | ROHM AND HAAS COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4082538-A | HERBICIDES FOR MONOCOTYLEDONS AND DICOTYLEDONS | ROHM AND HAAS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4076741-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4070178-A | Herbicidal diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1978-01-24 | — | — | US | disclosed |
| US-4063929-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4046798-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-4039588-A | ALKOXY, AMINO, HALO-, OR CYANO-SUBSTITUTED | ROHM AND HAAS COMPANY (US) | 1977-08-02 | — | — | US | disclosed |
| US-3954875-A | Benzophenone herbicides | ROHM AND HAAS COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3950379-A | HERBICIDES | ROHM AND HAAS COMPANY (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207145-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES | DDOST, DHX30, DDX5 | L3MBTL1 1494/4885EPHX1 152/4885EPHX2 217/4885 |
| US-20200352884-A1 | METHOD FOR INHIBITING OSTEOCLAST DEVELOPMENT | MSR1, MMP12, ARG1 | L3MBTL1 2647/4885EPHX1 994/4885EPHX2 808/4885 |
| US-11654123-B2 | Method for inhibiting osteoclast development | MSR1, MMP12, ARG1 | L3MBTL1 2647/4885EPHX1 994/4885EPHX2 808/4885 |
| US-20130303621-A1 | Method For Inhibiting Osteoclast Development | CCL11, ARG1, EPX | L3MBTL1 2793/4885EPHX1 448/4885EPHX2 425/4885 |
| US-11136315-B2 | CXCR2 antagonist | CXCR2, CXCR3, CXCR1 | L3MBTL1 4389/4885EPHX1 407/4885EPHX2 110/4885 |
| US-10682320-B2 | Method for inhibiting osteoclast development | CCL11, ARG1, EPX | L3MBTL1 2793/4885EPHX1 448/4885EPHX2 425/4885 |
| US-20170100385-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING DANIRIXIN FOR TREATING INFECTIOUS DISEASES | DDOST, DHX30, DDX5 | L3MBTL1 1494/4885EPHX1 152/4885EPHX2 217/4885 |
| US-20200339549-A1 | CXCR2 ANTAGONIST | CXCR2, CXCR3, CXCR1 | L3MBTL1 4389/4885EPHX1 407/4885EPHX2 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.