Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2A | O00443 | 1/20 | 0.36 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31081542 | 0.86 | ALDH1A1 (0.38) | PIK3C2APIK3C2BPIK3CAMTORALDH1A1 | |
| SCHEMBL31194355 | 0.84 | PIK3C2A (0.35) | PIK3C2APIK3C2BPIK3CAMTORALDH1A1 | |
| SCHEMBL25894966 | 0.83 | MAP4K4 (0.36) | PIK3C2APIK3C2BPIK3CAMTORALDH1A1 | |
| SCHEMBL30989642 | 0.83 | MAP4K4 (0.36) | PIK3C2APIK3C2BPIK3CAMTORALDH1A1 | |
| SCHEMBL25887409 | 0.78 | ALDH1A1 (0.39) | PIK3C2APIK3C2BPIK3CAMTORALDH1A1 | |
| SCHEMBL25887044 | 0.78 | PIK3C2A (0.34) | PIK3C2APIK3C2BPIK3CAMTORALDH1A1 | |
| SCHEMBL31194374 | 0.76 | KIT (0.33) | — | |
| SCHEMBL25886981 | 0.75 | PIK3C2A (0.38) | PIK3C2APIK3C2BPIK3CAMTORMAP4K1 | |
| SCHEMBL30122217 | 0.75 | POLB (0.42) | — | |
| SCHEMBL20628414 | 0.75 | POLB (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175557-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFOXIME-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |