Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2A | O00443 | 1/20 | 0.35 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21590020 | 0.91 | POLB (0.35) | POLB | |
| SCHEMBL31081648 | 0.86 | ALDH1A1 (0.37) | PIK3C2APIK3C2BPIK3CAMTORMAP4K1 | |
| SCHEMBL25886049 | 0.86 | ALDH1A1 (0.37) | PIK3C2APIK3C2BPIK3CAMTORMAP4K1 | |
| SCHEMBL21589986 | 0.85 | CYP1A2 (0.36) | POLBCYP1A2ALDH1A1 | |
| SCHEMBL20267583 | 0.85 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL30122217 | 0.85 | POLB (0.42) | POLBCYP1A2 | |
| SCHEMBL31194333 | 0.84 | PIK3C2A (0.36) | PIK3C2APIK3C2BPIK3CAMTORMAP4K1 | |
| SCHEMBL20628414 | 0.83 | POLB (0.40) | POLBCYP1A2 | |
| SCHEMBL30989642 | 0.83 | MAP4K4 (0.36) | PIK3C2APIK3C2BPIK3CAMTORMAP4K1 | |
| SCHEMBL25894966 | 0.83 | MAP4K4 (0.36) | PIK3C2APIK3C2BPIK3CAMTORMAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175557-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFOXIME-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |