SCHEMBL31194394

SCHEMBL31194394

NC(=O)c1cccc(-c2cccc(-c3cccc(C(N)=O)c3C(N)=O)c2)c1C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.55
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
IKBKB O14920 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
GAA P10253 1/20 0.42
SIRT2 Q8IXJ6 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
PARP1 P09874 4/20 0.41
CHEK1 O14757 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
PTGER1 P34995 1/20 0.40
PTGER4 P35408 1/20 0.40
PTGER3 P43115 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27688880 0.93 BCAT2 (0.58) BCAT2KEAP1NFE2L2IKBKBSIRT2
SCHEMBL27895545 0.90 PARP1 (0.49) BCAT2KEAP1NFE2L2IKBKBKDM4E
SCHEMBL901580 0.89 BCAT2 (0.71) BCAT2KEAP1NFE2L2IKBKBKDM4E
SCHEMBL402013 0.88 BCAT2 (0.56) BCAT2KEAP1NFE2L2KDM4EALDH1A1
SCHEMBL28442421 0.87 SLC6A2 (0.46) BCAT2KEAP1NFE2L2IKBKBKDM4E
SCHEMBL10908563 0.84 BCAT2 (0.77) BCAT2KEAP1NFE2L2IKBKBKDM4E
SCHEMBL7524098 0.83 BCAT2 (0.46) BCAT2KEAP1NFE2L2IKBKBKDM4E
SCHEMBL5608858 0.82 BCAT2 (0.61) BCAT2KEAP1NFE2L2KDM4EALDH1A1
SCHEMBL27895562 0.81 BCAT2 (0.52) BCAT2KEAP1NFE2L2IKBKBKDM4E
SCHEMBL18317987 0.81 HNF4A (0.56) BCAT2KEAP1NFE2L2IKBKBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024176223-A1 3D PRINTING BY IRRADIATION OF RECYCLABLE POLYMERS CONTAINING REVERSIBLE COVALENT BONDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-08-29 WO disclosed