SCHEMBL901580

SCHEMBL901580

NC(=O)c1cccc(-c2ccccc2)c1C(N)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 2/20 0.71
HNF4A P41235 1/20 0.52
KEAP1 Q14145 1/20 0.49
NFE2L2 Q16236 1/20 0.49
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
PARP1 P09874 3/20 0.46
IKBKB O14920 3/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
TSHR P16473 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.45
SIRT1 Q96EB6 1/20 0.45
CHRNB2 P17787 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29916354 0.91 BCAT2 (0.63) BCAT2HNF4AKEAP1NFE2L2NPC1
SCHEMBL570758 0.91 BCAT2 (0.63) BCAT2HNF4AKEAP1NFE2L2NPC1
SCHEMBL5968395 0.91 BCAT2 (0.69) BCAT2HNF4AKEAP1NFE2L2NPC1
SCHEMBL30481182 0.91 BCAT2 (0.69) BCAT2HNF4AKEAP1NFE2L2NPC1
SCHEMBL27688880 0.90 BCAT2 (0.58) BCAT2HNF4AKEAP1NFE2L2NPC1
SCHEMBL31194394 0.89 BCAT2 (0.55) BCAT2HNF4AKEAP1NFE2L2NPC1
SCHEMBL6842022 0.88 BCAT2 (0.63) BCAT2HNF4APARP1IKBKBMEN1
SCHEMBL402013 0.88 BCAT2 (0.56) BCAT2KEAP1NFE2L2PARP1KDM4E
SCHEMBL5608858 0.86 BCAT2 (0.61) BCAT2KEAP1NFE2L2NPC1RAB9A
SCHEMBL27895562 0.85 BCAT2 (0.52) BCAT2HNF4AKEAP1NFE2L2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112209835-A Method for preparing p-phenylenediamine 江苏方圆芳纶研究院有限公司 2021-01-12 CN claimed
CN-112194584-A Method for preparing 4-nitrosoaniline and 4-nitroaniline 江苏方圆芳纶研究院有限公司 2021-01-08 CN claimed
CN-107667441-B Flexible color filter device, flexible oganic light-emitting display device including the flexible color filter device and preparation method thereof 东友精细化工有限公司 2019-08-13 CN claimed
CN-108864034-A Amide aldehyde dehydrogenase agonist, and synthesis method and application thereof 中国人民解放军第二军医大学 2018-11-23 CN claimed
CN-107667441-A Flexible oganic light-emitting display device of flexible color filter device including the flexible color filter device and preparation method thereof 东友精细化工有限公司 2018-02-06 CN claimed
EP-2076121-A2 CROPPING SYSTEMS FOR MANAGING WEEDS Monsanto Technology, LLC (US) 2009-07-08 EP claimed
WO-2008051633-A2 CROPPING SYSTEMS FOR MANAGING WEEDS MONSANTO TECHNOLOGY LLC (US) 2008-05-02 WO claimed
CN-1057997-C Process for preparing p-nitroaromatic amides and products thereof SOLUTIA INC (US) 2000-11-01 CN claimed
US-5702610-A PASSING FLUID CONTAINING ANALYTE THROUGH SOLID PHASE EXTRACTION OR REACTION SHEET COMPRISING SORPTIVE POLYMER PULP HAVING PARTICLES ENMESHED THEREIN, WHEREIN ANALYTE BECOMES BOUND TO PULP OR PARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-12-30 US claimed
US-5688370-A ABSORPTIVE POLYMER PULP MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-11-18 US claimed
EP-0544561-B1 Ballistic resistant protection armour for the human body ETAT FRANCAIS REPR PAR MINISTE (FR) 1997-01-29 EP claimed
CN-1098402-A Preparation method and product thereof to the nitryl aromatic acid amides MONSANTO CO (US) 1995-02-08 CN claimed
EP-0401125-B1 Biphenyl derivatives, process for preparing the same and intermediates therefor TANABE SEIYAKU CO (JP) 1994-08-24 EP claimed
EP-0401125-A2 Biphenyl derivatives, process for preparing the same and intermediates therefor TANABE SEIYAKU CO., LTD. (JP) 1990-12-05 EP claimed
JP-4021508-A None JP disclosed
JP-6212073-A None JP disclosed
JP-63132938-A None JP disclosed
JP-H0421508-A PRODUCTION OF GRAPHITE FILM MATSUSHITA ELECTRIC IND CO LTD 1992-01-24 JP disclosed
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed
JP-S63132938-A AROMATIC POLYAMIDE AND PRODUCTION THEREOF TEIJIN LTD 1988-06-04 JP disclosed