Sugi Predict

Sugi Predict / Compounds / SCHEMBL311978

SCHEMBL311978

SCHEMBL311978

CC(C)(C)c1ccc2c(c1)-c1cc(C(C)(C)C)ccc1C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.45
▸ NPC1 O15118 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ PLA2G1B P04054 1/20 0.45
▸ NFKB1 P19838 1/20 0.45
▸ CASP3 P42574 1/20 0.45
▸ NFKB2 Q00653 1/20 0.45
▸ RELA Q04206 1/20 0.45
▸ SENP8 Q96LD8 1/20 0.45
▸ SENP7 Q9BQF6 1/20 0.45
▸ SENP6 Q9GZR1 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ ATG4B Q9Y4P1 1/20 0.45
▸ CYP1A2 P05177 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ MAPT P10636 3/20 0.43
▸ HPGD P15428 1/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471001 1.00 ALDH1A1 (0.45) ALDH1A1NPC1RAB9APLA2G1BNFKB1
Lithium SCHEMBL18315275 0.98 ALDH1A1 (0.44) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL18315273 0.98 ALDH1A1 (0.44) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL3171441 0.90 ALDH1A1 (0.52) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL40372 0.86 ALDH1A1 (0.45) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL29459210 0.86 ALDH1A1 (0.45) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL3890954 0.85 ALDH1A1 (0.36) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL6552336 0.84 ALDH1A1 (0.44) ALDH1A1NPC1RAB9APLA2G1BNFKB1
Lithium SCHEMBL6552341 0.84 ALDH1A1 (0.44) ALDH1A1NPC1RAB9APLA2G1BNFKB1
SCHEMBL6903879 0.83 ALDH1A1 (0.44) ALDH1A1NPC1RAB9APLA2G1BNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110218274-B Preparation method of ethylene-conjugated diene random copolymer 中国科学院长春应用化学研究所 2020-07-31 — — CN claimed
CN-110256622-A A kind of activeness and quietness syndiotactic polytyrene and preparation method thereof 中国科学院长春应用化学研究所 2019-09-20 — — CN claimed
CN-110218274-A A kind of preparation method of ethylene-conjugated diene random copolymer 中国科学院长春应用化学研究所 2019-09-10 — — CN claimed
US-8288602-B2 Synthesis of substituted fluorene ligands TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2012-10-16 — — US claimed
US-8093418-B2 Metallocenes; for production of ethylene/propylene homo-/copolymers FINA TECHNOLOGY, INC. (US) 2012-01-10 — — US claimed
US-20110009683-A1 SYNTHESIS OF SUBSTITUTED FLUORENE LIGANDS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-01-13 — — US claimed
EP-1999091-B1 SYNTHESIS OF SUBSTITUTED FLUORENES TOTAL PETROCHEMICALS RES FELUY (BE) 2010-08-04 — — EP claimed
EP-1999091-A2 SYNTHESIS OF SUBSTITUTED FLUORENES TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-12-10 — — EP claimed
US-20080026935-A1 Preparation and Use of Tetrasubstituted Fluorenyl Catalysts for Polymerization of Olefins FINA TECHNOLOGY, INC. (US) 2008-01-31 — — US claimed
WO-2007111537-A2 SYNTHESIS OF SUBSTITUTED FLUORENES GOSUDARSTVENNOE UCHEBNO-NAUCHNOE UCHREZHDENIE KHIMICHESKY FAKULTET MOSKOVSKOGO GOSUDARSTVENNOGO UNIVERSITETA IM. M.V.LOMONOSOVA (RU) 2007-10-04 — — WO claimed
US-20070043183-A1 Preparation and use of tetrasubstituted fluorenyl catalysts for polymerization of olefins FINA TECHNOLOGY, INC. 2007-02-22 — — US claimed
US-20240010760-A1 TRANSITION METAL COMPOUND, CATALYST COMPRISING SAME, AND METHOD FOR PREPARING SAME Hanwha Solutions Corporation (KR) 2024-01-11 — — US disclosed
CN-114380850-B Gold-containing metal complexes, mixtures, compositions and organic electronic devices 广州华睿光电材料有限公司 2023-11-28 — — CN disclosed
US-11760819-B2 Ethylene α-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof MITSUI CHEMICALS, INC. (JP) 2023-09-19 — — US disclosed
CN-116457362-A Transition metal compound, catalyst comprising same, and method for producing same 韩华思路信株式会社 2023-07-18 — — CN disclosed
EP-1083188-A1 Catalyst and process for the preparation of syndiotactic / atactic block polyolefins FINA RESEARCH S.A. (BE) 2001-03-14 — — EP disclosed
US-6057258-A Solid catalytic component for the polymerization of olefins ELF ATOCHEM S.A. (FR) 2000-05-02 — — US disclosed
EP-0889065-A1 Solid catalyst component for the polymerisation of olefins ELF ATOCHEM S.A. (FR) 1999-01-07 — — EP disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 — — US disclosed
EP-0666267-A2 Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 1995-08-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009683-A1 SYNTHESIS OF SUBSTITUTED FLUORENE LIGANDS FDPS, FLNB, PFAS ALDH1A1 2283/4885NPC1 534/4885RAB9A 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.