SCHEMBL3119876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23715914	0.83	CYP1A2 (0.48)	CYP1A2CYP2A6PDE10AHTR2BL3MBTL1
	SCHEMBL21363719	0.83	CYP2A6 (0.50)	CYP1A2CYP2A6PDE10AHTR2CHTR2B
	SCHEMBL3121339	0.83	HTR2B (0.50)	CYP1A2CYP2A6PDE10AHTR2BL3MBTL1
	SCHEMBL3121450	0.81	HTR2C (0.42)	PDE10AHTR2CHTR2BL3MBTL1ATM
	SCHEMBL21951174	0.75	CYP1A2 (0.44)	CYP1A2CYP2A6PDE10AHTR2BL3MBTL1
	SCHEMBL3128182	0.75	PDE10A (0.52)	CYP1A2CYP2A6PDE10AHTR2CHTR2B
	SCHEMBL21142106	0.75	CYP2C19 (0.60)	CYP1A2FYNL3MBTL1CYP2C19ALDH1A1
	SCHEMBL30638836	0.75	CYP2C19 (0.60)	CYP1A2FYNL3MBTL1CYP2C19ALDH1A1
	SCHEMBL3129580	0.74	SLC6A2 (0.44)	PDE10AL3MBTL1ATMCYP2C19ALDH1A1
	SCHEMBL3116975	0.74	NPC1 (0.55)	CYP1A2CYP2A6PDE10AFYNL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.