SCHEMBL3116975

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28771177	0.84	PDE10A (0.55)	NPC1RAB9ACYP11B1CYP11B2LTA4H
	SCHEMBL23715914	0.83	CYP1A2 (0.48)	NPC1RAB9ACYP11B1CYP11B2PDE10A
	SCHEMBL3121339	0.83	HTR2B (0.50)	RAB9ACYP11B1CYP11B2LTA4HPDE10A
	SCHEMBL17664092	0.80	HSP90AB1 (0.47)	PDE10ASMN1; SMN2ATMLMNAL3MBTL1
	SCHEMBL28844860	0.79	KMT2A (0.49)	NPC1RAB9AALDH1A1SMN1; SMN2LMNA
	SCHEMBL28903971	0.77	NPC1 (0.51)	NPC1RAB9ACYP11B1CYP11B2LTA4H
	SCHEMBL6982798	0.76	L3MBTL1 (0.41)	NPC1CYP11B1CYP11B2PDE10AATM
	SCHEMBL27425206	0.76	NPC1 (0.56)	NPC1RAB9ALTA4HPDE10APOLB
	SCHEMBL509565	0.76	APP (0.50)	CYP11B1CYP11B2LTA4HPDE10AALDH1A1
	Ammonia Solution, Strong SCHEMBL28903975	0.76	PDE3B (0.49)	CYP11B1CYP11B2LTA4HPDE10AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.