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SCHEMBL31199673

SCHEMBL31199673

CCc1cc(C)cc(O)c1-c1ccc(N2CCO[C@H](CO)C2)nn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 2/20 0.39
▸ PIK3CA P42336 2/20 0.39
▸ PIK3CB P42338 2/20 0.39
▸ PIK3CG P48736 2/20 0.39
▸ LRRK2 Q5S007 4/20 0.38
▸ CNR2 P34972 2/20 0.37
▸ SYK P43405 2/20 0.36
▸ NLRP3 Q96P20 2/20 0.36
▸ IL1B P01584 1/20 0.36
▸ ADORA2A P29274 1/20 0.36
▸ ADORA1 P30542 1/20 0.36
▸ AKT1 P31749 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ THRB P10828 1/20 0.35
▸ PIK3C2B O00750 1/20 0.34
▸ MTOR P42345 1/20 0.34
▸ RAF1 P04049 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31199314 0.90 IL1B (0.45) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199817 0.90 IL1B (0.45) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199386 0.87 PIK3CD (0.41) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199293 0.87 AKT1 (0.37) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199489 0.87 IL1B (0.42) CNR2NLRP3IL1BRAF1BRAF
SCHEMBL31199666 0.87 LRRK2 (0.37) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199453 0.85 NLRP3 (0.38) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199399 0.85 PIK3CD (0.43) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199471 0.83 CNR2 (0.44) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2
SCHEMBL31199588 0.83 AKT1 (0.40) PIK3CDPIK3CAPIK3CBPIK3CGLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680601-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES Sanofi (FR) 2026-01-21 — — EP claimed
US-20240360151-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES SANOFI (FR) 2024-10-31 — — US claimed
WO-2024188994-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES SANOFI (FR) 2024-09-19 — — WO claimed
EP-4680601-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES Sanofi (FR) 2026-01-21 — — EP disclosed
US-20240360151-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES SANOFI (FR) 2024-10-31 — — US disclosed
WO-2024188994-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES SANOFI (FR) 2024-09-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360151-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES NLRP3, NOD1, NLRP1 PIK3CD 3591/4885PIK3CA 2887/4885PIK3CB 3446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.