Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31200129 | 0.85 | DPP4 (0.39) | DPP4DPP8CHRM2CHRM4 | |
| SCHEMBL31200314 | 0.84 | TAS2R14 (0.43) | TAS2R14 | |
| SCHEMBL31196318 | 0.79 | JAK2 (0.48) | — | |
| SCHEMBL31200177 | 0.77 | CYP2C9 (0.40) | TAS2R14 | |
| SCHEMBL22278140 | 0.76 | CHKA (0.44) | DPP4DPP8 | |
| SCHEMBL31200363 | 0.76 | TRPM8 (0.39) | TAS2R14 | |
| SCHEMBL31200379 | 0.74 | PLK4 (0.37) | TAS2R14 | |
| SCHEMBL31200370 | 0.74 | PLK4 (0.37) | TAS2R14 | |
| SCHEMBL15422809 | 0.74 | PLG (0.43) | CHRM2TAS2R14 | |
| SCHEMBL31200300 | 0.74 | TAS2R14 (0.37) | TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709722-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233547-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |