SCHEMBL31200403

SCHEMBL31200403

Cc1nc([C@@H]2CCON2)co1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31205754 0.98 ENPP3 (0.32) ENPP3ENPP1
SCHEMBL21009025 0.71
SCHEMBL22210926 0.70 OPRK1 (0.31)
SCHEMBL31200163 0.70 OPRK1 (0.31)
Hydrochloric Acid SCHEMBL25262088 0.70
SCHEMBL22632134 0.69 ENPP3 (0.35) ENPP3ENPP1IDH1
SCHEMBL2262247 0.67 L3MBTL1 (0.38) ENPP3ENPP1IDH1
SCHEMBL25300599 0.67 CHRM2 (0.32)
SCHEMBL31200250 0.63 NISCH (0.33)
SCHEMBL31200243 0.63 GFER (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709722-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2026-03-18 EP disclosed
WO-2024233547-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2024-11-14 WO disclosed