SCHEMBL31201329

SCHEMBL31201329

CCC(CC)Nc1cc(Nc2ccncc2)c2nnc(C3CC3)n2n1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 2/20 0.33
▸ GABRA1 P14867 3/20 0.32
▸ GABRG2 P18507 3/20 0.32
▸ GABRB3 P28472 3/20 0.32
▸ GABRA5 P31644 3/20 0.32
▸ GABRA3 P34903 3/20 0.32
▸ GABRA2 P47869 3/20 0.32
▸ CCNA2 P20248 4/20 0.32
▸ CDK2 P24941 4/20 0.32
▸ CDK5 Q00535 4/20 0.32
▸ DYRK1A Q13627 4/20 0.32
▸ CDK5R1 Q15078 4/20 0.32
▸ CCNA1 P78396 2/20 0.32
▸ DYRK3 O43781 2/20 0.31
▸ CCNT1 O60563 2/20 0.31
▸ CDK9 P50750 2/20 0.31
▸ DYRK2 Q92630 2/20 0.31
▸ DYRK1B Q9Y463 2/20 0.31
▸ MKNK1 Q9BUB5 1/20 0.31
▸ MALT1 Q9UDY8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31201482 0.92 GABRA1 (0.34) BRD4GABRA1GABRG2GABRB3GABRA5
SCHEMBL31201295 0.90 CCNA2 (0.34) BRD4GABRA1GABRG2GABRB3GABRA5
SCHEMBL31201340 0.89 CCNA2 (0.39) BRD4GABRA1GABRG2GABRB3GABRA5
SCHEMBL31201308 0.88 PDE10A (0.31) CCNA2CDK2CDK5DYRK1ACDK5R1
SCHEMBL31201366 0.88 CCNA2 (0.35) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL31201167 0.85 GABRA1 (0.36) BRD4GABRA1GABRG2GABRB3GABRA5
SCHEMBL31201371 0.85 PDE10A (0.33) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL31201155 0.85 GABRA1 (0.33) BRD4GABRA1GABRG2GABRB3GABRA5
SCHEMBL31201351 0.85 GABRG2 (0.41) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL31201327 0.84 FLT3 (0.35) BRD4GABRA1GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727944-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT Perha Pharmaceuticals (FR) 2026-04-22 — — EP claimed
WO-2024256496-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT PERHA PHARMACEUTICALS (FR) 2024-12-19 — — WO claimed
EP-4477653-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT Perha Pharmaceuticals (FR) 2024-12-18 — — EP claimed
EP-4727944-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT Perha Pharmaceuticals (FR) 2026-04-22 — — EP disclosed
WO-2024256496-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT PERHA PHARMACEUTICALS (FR) 2024-12-19 — — WO disclosed
EP-4477653-A1 [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT Perha Pharmaceuticals (FR) 2024-12-18 — — EP disclosed
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