Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 4/20 | 0.39 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31201482 | 0.89 | GABRA1 (0.34) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201329 | 0.89 | BRD4 (0.33) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201308 | 0.88 | PDE10A (0.31) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201295 | 0.87 | CCNA2 (0.34) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201371 | 0.84 | PDE10A (0.33) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201155 | 0.84 | GABRA1 (0.33) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201156 | 0.84 | OGA (0.37) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201513 | 0.83 | CCNA2 (0.40) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201167 | 0.83 | GABRA1 (0.36) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL31201351 | 0.82 | GABRG2 (0.41) | CCNA2CDK2CDK5DYRK1ACDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | claimed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | claimed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | claimed |
| EP-4727944-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256496-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | PERHA PHARMACEUTICALS (FR) | 2024-12-19 | — | — | WO | disclosed |
| EP-4477653-A1 | [1,2,4]-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES USEFUL AS A MEDICAMENT | Perha Pharmaceuticals (FR) | 2024-12-18 | — | — | EP | disclosed |