Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17231383 | 0.80 | ADRB2 (0.44) | RXFP1KLKB1LMNALTB4RTDP1 | |
| SCHEMBL11583604 | 0.79 | KDM4E (0.51) | RXFP1KLKB1LMNALTB4RPIK3CD | |
| SCHEMBL553847 | 0.75 | KLKB1 (0.53) | RXFP1KLKB1LMNATDP2KDM4C | |
| SCHEMBL23337069 | 0.72 | KLKB1 (0.54) | RXFP1KLKB1LTB4RMEN1KMT2A | |
| SCHEMBL31201754 | 0.71 | TDP2 (0.51) | LTB4RTDP1TDP2KDM4CCALM1 | |
| SCHEMBL9285055 | 0.71 | GAA (0.47) | LMNAALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL14415474 | 0.70 | TDP2 (0.50) | RXFP1LTB4RTDP1TDP2KDM4C | |
| SCHEMBL11295802 | 0.69 | TDP2 (0.49) | RXFP1LMNALTB4RTDP2KDM4C | |
| SCHEMBL30993366 | 0.69 | — | — | |
| SCHEMBL27217204 | 0.68 | NR1H3 (0.63) | TDP2KDM4CHSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233642-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |