Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADCY10 | Q96PN6 | 3/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11296201 | 0.85 | HTR6 (0.41) | TDP2KDM4CALDH1A1ADCY10HTR6 | |
| SCHEMBL14415474 | 0.85 | TDP2 (0.50) | TDP2KDM4CALDH1A1TSHRNR1H2 | |
| SCHEMBL31201754 | 0.76 | TDP2 (0.51) | TDP2KDM4CALDH1A1TSHRNR1H2 | |
| SCHEMBL11330915 | 0.70 | PKM (0.45) | ALDH1A1MEN1KMT2ALMNALTB4R | |
| SCHEMBL17231383 | 0.70 | ADRB2 (0.44) | TDP2KDM4CTSHRNR1H2NR1H3 | |
| SCHEMBL31201752 | 0.69 | RXFP1 (0.41) | TDP2KDM4CALDH1A1TSHRMEN1 | |
| SCHEMBL11583604 | 0.69 | KDM4E (0.51) | ALDH1A1ADCY10HTR6HRH4LMNA | |
| SCHEMBL2614741 | 0.66 | CALM1 (0.61) | ALDH1A1TSHRMEN1KMT2AHTR6 | |
| SCHEMBL553847 | 0.66 | KLKB1 (0.53) | TDP2KDM4CNR1H2NR1H3ADCY10 | |
| SCHEMBL6969973 | 0.66 | NR1H3 (0.58) | KDM4CNR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065217-A2 | 5-Haloalkyl-1,2,4-triazole and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-11-24 | — | — | EP | disclosed |