Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | USP14 | P54578 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855497 | 0.86 | IDO1 (0.56) | IDO1ALDH1A1KMT2ARXRARXRB | |
| SCHEMBL12095650 | 0.84 | DUT (0.33) | IDO1ALDH1A1LMNA | |
| SCHEMBL2358011 | 0.83 | TAAR1 (0.34) | IDO1ESR1ESR2KMT2ABACE1 | |
| SCHEMBL10511243 | 0.83 | IDO1 (0.41) | IDO1ESR1ESR2 | |
| SCHEMBL12840828 | 0.83 | CYP4F2 (0.42) | IDO1ESR1ESR2KMT2ABACE1 | |
| SCHEMBL2882196 | 0.81 | PTGS2 (0.51) | ESR1LMNATSHRHTTKMT2A | |
| SCHEMBL906834 | 0.80 | IDO1 (0.48) | IDO1ESR1ESR2LMNAHPGD | |
| SCHEMBL3178345 | 0.79 | PPARG (0.40) | IDO1ALDH1A1ESR1HPGDTSHR | |
| SCHEMBL15489965 | 0.77 | TDP1 (0.37) | ALDH1A1KMT2ABACE1RXRARXRB | |
| SCHEMBL12855670 | 0.77 | AGXT (0.52) | IDO1TSHRUSP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233642-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |