SCHEMBL31202243

SCHEMBL31202243

NNc1ccc(C(=O)O)cc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
ALDH1A1 P00352 5/20 0.61
AKR1C3 P42330 11/20 0.53
AKR1C2 P52895 11/20 0.53
AKR1B10 O60218 1/20 0.51
AKR1B1 P15121 1/20 0.51
AKR1C4 P17516 1/20 0.51
AKR1C1 Q04828 1/20 0.51
KDM4E B2RXH2 5/20 0.48
GAA P10253 4/20 0.47
THRB P10828 3/20 0.47
HPGD P15428 3/20 0.47
HTT P42858 2/20 0.47
GFER P55789 2/20 0.47
HSD17B10 Q99714 2/20 0.47
PLEC Q15149 1/20 0.47
KDM5A P29375 1/20 0.46
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28900448 0.86 AKR1C3 (0.49) MAPTALDH1A1AKR1C3AKR1C2AKR1B10
SCHEMBL9472568 0.86 MAPT (0.65) MAPTALDH1A1AKR1C3AKR1C2AKR1B10
SCHEMBL1002161 0.85 MAPT (0.69) MAPTALDH1A1KDM4EGAATHRB
SCHEMBL8340169 0.83 AKR1C3 (0.53) MAPTALDH1A1AKR1C3AKR1C2AKR1B10
SCHEMBL7540135 0.82 LTC4S (0.51) MAPTALDH1A1AKR1C3AKR1C2AKR1B10
SCHEMBL9064899 0.82 GAA (0.64) MAPTALDH1A1KDM4EGAATHRB
SCHEMBL17938282 0.82 MAPT (0.57) MAPTALDH1A1AKR1C3AKR1C2AKR1B10
SCHEMBL20604900 0.80 MAPT (0.58) MAPTALDH1A1KDM4EGAATHRB
SCHEMBL6235537 0.80 ALDH1A1 (0.58) MAPTALDH1A1KDM4EGAATHRB
SCHEMBL7976731 0.80 ALDH1A1 (0.73) MAPTALDH1A1KDM4EGAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118961860-A Application of 2, 4-dicarboxyphenyl hydrazine as reactive matrix in mass calibration of MALDI mass spectrum negative ion mode and N-glycan analysis 浙江大学 2024-11-15 CN claimed
CN-118961860-B Application of 2, 4-dicarboxyphenyl hydrazine as reactive matrix in mass calibration of MALDI mass spectrum negative ion mode and N-glycan analysis 浙江大学 2025-09-16 CN disclosed
CN-118961860-B Application of 2, 4-dicarboxyphenyl hydrazine as reactive matrix in mass calibration of MALDI mass spectrum negative ion mode and N-glycan analysis 浙江大学 2025-09-16 CN disclosed
CN-118961860-A Application of 2, 4-dicarboxyphenyl hydrazine as reactive matrix in mass calibration of MALDI mass spectrum negative ion mode and N-glycan analysis 浙江大学 2024-11-15 CN disclosed
CN-118961860-A Application of 2, 4-dicarboxyphenyl hydrazine as reactive matrix in mass calibration of MALDI mass spectrum negative ion mode and N-glycan analysis 浙江大学 2024-11-15 CN disclosed
CN-118961860-A Application of 2, 4-dicarboxyphenyl hydrazine as reactive matrix in mass calibration of MALDI mass spectrum negative ion mode and N-glycan analysis 浙江大学 2024-11-15 CN disclosed