Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31205847 | 0.89 | RIPK1 (0.39) | RIPK1KDM4ETSHRACACB | |
| SCHEMBL31205747 | 0.88 | RIPK1 (0.39) | RIPK1KDM4ETSHRACACB | |
| SCHEMBL31205434 | 0.86 | RIPK1 (0.39) | RIPK1KDM4EMTOR | |
| SCHEMBL31205790 | 0.83 | RIPK1 (0.42) | RIPK1KDM4E | |
| SCHEMBL31205850 | 0.83 | RIPK1 (0.42) | RIPK1KDM4E | |
| SCHEMBL31205686 | 0.83 | RIPK1 (0.38) | RIPK1KDM4EMTOR | |
| SCHEMBL31205685 | 0.83 | RIPK1 (0.38) | RIPK1KDM4EMTOR | |
| SCHEMBL31205739 | 0.83 | RIPK1 (0.38) | RIPK1KDM4ETSHRACACB | |
| SCHEMBL31205525 | 0.82 | RIPK1 (0.40) | RIPK1KDM4EMTOR | |
| SCHEMBL31205861 | 0.81 | RIPK1 (0.37) | RIPK1KDM4EACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709723-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | claimed |
| WO-2024233544-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | claimed |
| EP-4709723-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233544-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |