Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296814 | 0.88 | ALDH1A1 (0.36) | TSHRDDB1CRBNPOLB | |
| SCHEMBL30547542 | 0.88 | ALDH1A1 (0.36) | TSHRDDB1CRBNPOLB | |
| SCHEMBL25816524 | 0.83 | KMT2A (0.35) | GPR119MEN1MAPTTSHRKMT2A | |
| SCHEMBL18921291 | 0.81 | DGAT1 (0.38) | DGAT1WNT3AGPR119MEN1MAPT | |
| SCHEMBL29966718 | 0.81 | DGAT1 (0.38) | DGAT1WNT3AGPR119MEN1MAPT | |
| SCHEMBL31205916 | 0.81 | DPP4 (0.34) | GPR119MAPTTSHRPOLBCYP1A2 | |
| SCHEMBL25816371 | 0.81 | GPR119 (0.36) | GPR119SMN1; SMN2CYP3A4 | |
| SCHEMBL29966472 | 0.80 | DGAT1 (0.39) | DGAT1WNT3AGPR119MEN1MAPT | |
| SCHEMBL30547503 | 0.80 | DGAT1 (0.39) | DGAT1WNT3AGPR119MEN1MAPT | |
| SCHEMBL29048248 | 0.80 | DGAT1 (0.39) | DGAT1WNT3AGPR119MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709723-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233544-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |