Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 12/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786255 | 0.84 | MAP3K5 (0.36) | CYP4F2CYP4A11IDO1RETATR | |
| SCHEMBL31131749 | 0.81 | CYP4F2 (0.40) | CYP4F2CYP4A11IDO1RETATR | |
| SCHEMBL24552673 | 0.80 | CYP4F2 (0.35) | CYP4F2CYP4A11RETATRRXRA | |
| SCHEMBL29732489 | 0.79 | RET (0.36) | CYP4F2CYP4A11RETRXRARXRB | |
| SCHEMBL30570060 | 0.79 | ALDH1A1 (0.39) | CYP4F2CYP4A11RETATRRXRA | |
| SCHEMBL24552691 | 0.79 | RET (0.36) | CYP4F2CYP4A11RETRXRARXRB | |
| SCHEMBL31391657 | 0.79 | CYP4F2 (0.39) | CYP4F2CYP4A11IDO1RETATR | |
| SCHEMBL14493344 | 0.77 | CYP4F2 (0.37) | CYP4F2CYP4A11RETATRRXRA | |
| SCHEMBL30673111 | 0.77 | MAPT (0.36) | CYP4F2CYP4A11RETATRRXRA | |
| SCHEMBL26924742 | 0.77 | MAPT (0.36) | CYP4F2CYP4A11RETATRRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024229091-A1 | EGFR INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-11-07 | — | — | WO | disclosed |