Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 2/20 | 0.34 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16101090 | 0.88 | MAP3K5 (0.36) | MAP3K5PER2CRY1CRY2RET | |
| SCHEMBL30775616 | 0.88 | MAP3K5 (0.36) | MAP3K5PER2CRY1CRY2RET | |
| SCHEMBL31206321 | 0.84 | CYP4F2 (0.38) | RETCYP4F2CYP4A11RXRARXRB | |
| SCHEMBL14493344 | 0.83 | CYP4F2 (0.37) | RETCYP4F2CYP4A11RXRARXRB | |
| SCHEMBL26924742 | 0.83 | MAPT (0.36) | RETCYP4F2CYP4A11RXRARXRB | |
| SCHEMBL30673111 | 0.83 | MAPT (0.36) | RETCYP4F2CYP4A11RXRARXRB | |
| SCHEMBL29705188 | 0.81 | FGFR1 (0.38) | MAP3K5RETCYP4F2CYP4A11PARP1 | |
| SCHEMBL18198891 | 0.81 | FGFR1 (0.38) | MAP3K5RETCYP4F2CYP4A11PARP1 | |
| SCHEMBL31190737 | 0.80 | DGAT2 (0.36) | MAP3K5RETDGAT2CYP4F2CYP4A11 | |
| SCHEMBL31411379 | 0.80 | ESR1 (0.40) | MAP3K5RETCYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |