Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249745 | 0.92 | GAA (0.49) | GAATSHRKMT2AMAPTTDP1 | |
| SCHEMBL3237347 | 0.89 | GAA (0.48) | GAATSHRMAPTTDP1SMN1; SMN2 | |
| SCHEMBL3126815 | 0.88 | GAA (0.51) | GAATSHRKMT2AMAPTTDP1 | |
| SCHEMBL3119103 | 0.85 | GAA (0.42) | GAATSHRKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL3241489 | 0.81 | TSHR (0.46) | GAATSHRKMT2AMAPTTDP1 | |
| SCHEMBL13521588 | 0.80 | TSHR (0.52) | GAATSHRKMT2AMAPTMEN1 | |
| SCHEMBL3252753 | 0.80 | TSHR (0.44) | GAATSHRKMT2AMAPTTDP1 | |
| SCHEMBL3248197 | 0.80 | TSHR (0.46) | GAATSHRKMT2AMAPTTDP1 | |
| SCHEMBL13521713 | 0.80 | TSHR (0.44) | GAATSHRKMT2AMAPTTDP1 | |
| SCHEMBL3240895 | 0.79 | TAAR1 (0.43) | GAATSHRKMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |
| WO-2010008777-A2 | FUSED AZABICYCLIC PYRIDINES | LIGAND PHARMACEUTICALS INC. (US) | 2010-01-21 | — | — | WO | disclosed |