SCHEMBL312079

SCHEMBL312079

C=Cc1ccc2c3ccccc3c3ccccc3c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 2/20 0.43
TP53 P04637 1/20 0.43
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CCNB2 O95067 2/20 0.38
CDK1 P06493 2/20 0.38
CCNB1 P14635 2/20 0.38
GSK3A P49840 2/20 0.38
GSK3B P49841 2/20 0.38
CDK5 Q00535 2/20 0.38
CDK5R1 Q15078 2/20 0.38
CCNB3 Q8WWL7 2/20 0.38
TRPA1 O75762 1/20 0.36
HPRT1 P00492 3/20 0.36
KIF11 P52732 2/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TYMS P04818 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL311941 0.82 ALDH1A1 (0.46) ALDH1A1TSHRTDP1TP53CCNB2
SCHEMBL27686717 0.81 HPRT1 (0.56) ALDH1A1TSHRTDP1HPRT1MEN1
SCHEMBL38666753 0.79 ALDH1A1 (0.56) ALDH1A1TSHRTDP1TP53HPRT1
SCHEMBL1778036 0.79 ALDH1A1 (0.56) ALDH1A1TSHRTDP1TP53HPRT1
SCHEMBL21390522 0.79 MEN1 (0.40) ALDH1A1TSHRMEN1KMT2AMAPT
SCHEMBL5599572 0.79 ALDH1A1 (0.43) ALDH1A1TSHRTDP1TP53ESR1
SCHEMBL31340108 0.78 ALDH1A1 (0.46) ALDH1A1TSHRTDP1TP53ESR1
SCHEMBL12110644 0.78 KDM4E (0.42) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL449311 0.78 ALDH1A1 (0.54) ALDH1A1TSHRTDP1HPRT1MEN1
SCHEMBL24741417 0.78 PTGS2 (0.39) ALDH1A1TSHRTDP1TP53ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3064563-B1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2018-12-26 EP disclosed
EP-3064563-A1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2016-09-07 EP disclosed
EP-2277978-B1 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORP (US) 2016-03-30 EP disclosed
US-9139494-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2015-09-22 US disclosed
US-8580404-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-11-12 US disclosed
US-20130001538-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION (US) 2013-01-03 US disclosed
EP-1888708-B1 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORP (US) 2012-11-21 EP disclosed
US-20120032156-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION 2012-02-09 US disclosed
US-8092924-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-01-10 US disclosed
EP-2277978-A2 Triphenylene hosts in phosphorescent light emitting diodes Universal Display Corporation (US) 2011-01-26 EP disclosed
EP-1888708-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2008-02-20 EP disclosed
US-20060280965-A1 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION 2006-12-14 US disclosed
WO-2006130598-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2006-12-07 WO disclosed