SCHEMBL311941

SCHEMBL311941

C=Cc1ccc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
HDAC2 Q92769 1/20 0.41
PTGS2 P35354 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PIK3CG P48736 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
GSK3B P49841 2/20 0.33
CHEK1 O14757 2/20 0.33
JAK2 O60674 2/20 0.33
DAPK3 O43293 1/20 0.33
ABL1 P00519 1/20 0.33
NTRK1 P04629 1/20 0.33
FYN P06241 1/20 0.33
CSF1R P07333 1/20 0.33
RET P07949 1/20 0.33
MET P08581 1/20 0.33
PDGFRB P09619 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8758894 0.82 ALDH1A1 (0.48) ALDH1A1TSHRHDAC2MEN1KMT2A
SCHEMBL312079 0.82 ALDH1A1 (0.48) ALDH1A1TSHRHDAC2MEN1KMT2A
SCHEMBL24741417 0.82 PTGS2 (0.39) ALDH1A1TSHRHDAC2PTGS2TDP1
SCHEMBL5888641 0.81 ALDH1A1 (0.47) ALDH1A1TSHRHDAC2MEN1KMT2A
SCHEMBL21390343 0.79 PTGS2 (0.38) ALDH1A1HDAC2PTGS2MEN1KMT2A
SCHEMBL10023271 0.79 KIF11 (0.47) ALDH1A1KIF11
SCHEMBL14353699 0.79 CHEK1 (0.50) ALDH1A1CHEK1CDK1
SCHEMBL14353702 0.79 CHEK1 (0.50) ALDH1A1CHEK1CDK1
SCHEMBL4133589 0.79 HPRT1 (0.45) ALDH1A1TSHRTDP1JAK2HPRT1
SCHEMBL8758599 0.78 ALDH1A1 (0.56) ALDH1A1TSHRHDAC2PTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120032156-A1 Triphenylene Hosts in Phosphorescent Light Emitting Diodes UNIVERSAL DISPLAY CORPORATION 2012-02-09 US disclosed
US-8092924-B2 Triphenylene hosts in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-01-10 US disclosed
EP-2277978-A2 Triphenylene hosts in phosphorescent light emitting diodes Universal Display Corporation (US) 2011-01-26 EP disclosed
EP-1888708-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2008-02-20 EP disclosed
WO-2006130598-A2 TRIPHENYLENE HOSTS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2006-12-07 WO disclosed