Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298575 | 1.00 | LMNA (0.44) | LMNAKDM4EPKMMAPTTSHR | |
| SCHEMBL31207901 | 1.00 | LMNA (0.44) | LMNAKDM4EPKMMAPTTSHR | |
| SCHEMBL537829 | 0.94 | MAPT (0.48) | LMNAKDM4EPKMMAPTTSHR | |
| SCHEMBL18305004 | 0.89 | LMNA (0.49) | LMNAKDM4EPKMMAPTTSHR | |
| SCHEMBL9124409 | 0.86 | MAPT (0.43) | LMNAKDM4EPKMMAPTTSHR | |
| SCHEMBL22573664 | 0.85 | KDM4E (0.49) | LMNAKDM4EPKMMAPTTSHR | |
| SCHEMBL24785780 | 0.84 | TSHR (0.42) | LMNAKDM4ETSHRALDH1A1HPGD | |
| SCHEMBL30558073 | 0.84 | ALDH1A1 (0.41) | LMNAKDM4EMAPTTSHRALDH1A1 | |
| SCHEMBL25366832 | 0.84 | ALDH1A1 (0.41) | LMNAKDM4EMAPTTSHRALDH1A1 | |
| SCHEMBL1298124 | 0.83 | LMNA (0.44) | LMNAKDM4EPKMMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122074043-A | Combination therapy with KRAS modulators | 光达治疗公司 | 2026-05-22 | — | — | CN | disclosed |
| CN-119110804-A | KRAS modulators and uses thereof | 光达治疗公司 | 2024-12-10 | — | — | CN | disclosed |