Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NMT2 | O60551 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537829 | 0.92 | MAPT (0.48) | MAPTTSHRLMNAMAPK1NPSR1 | |
| SCHEMBL14407169 | 0.90 | MAPT (0.41) | MAPTTSHRLMNAADORA3MAPK1 | |
| SCHEMBL31207902 | 0.86 | LMNA (0.44) | MAPTTSHRLMNAADORA3MAPK1 | |
| SCHEMBL1298575 | 0.86 | LMNA (0.44) | MAPTTSHRLMNAADORA3MAPK1 | |
| SCHEMBL31207901 | 0.86 | LMNA (0.44) | MAPTTSHRLMNAADORA3MAPK1 | |
| SCHEMBL22573664 | 0.84 | KDM4E (0.49) | MAPTTSHRLMNAMAPK1NPSR1 | |
| SCHEMBL15155090 | 0.83 | ADORA3 (0.49) | MAPTLMNAADORA3NPSR1HPGD | |
| SCHEMBL25366832 | 0.82 | ALDH1A1 (0.41) | MAPTTSHRLMNAMAPK1NPSR1 | |
| SCHEMBL30558073 | 0.82 | ALDH1A1 (0.41) | MAPTTSHRLMNAMAPK1NPSR1 | |
| SCHEMBL25366055 | 0.81 | MAPT (0.41) | MAPTTSHRLMNAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439911-A | A potent fungicides, insecticides and miticides | SHIONOGI & CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0606011-A1 | Aminopyrimidine derivatives and their production and use | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |