Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207938 | 0.90 | BRS3 (0.37) | EIF4EEIF4EBP1BRS3GABRPGABRD | |
| SCHEMBL25308857 | 0.90 | BRS3 (0.37) | EIF4EEIF4EBP1BRS3GABRPGABRD | |
| SCHEMBL31207933 | 0.78 | NNMT (0.37) | BRS3POLQ | |
| SCHEMBL22717450 | 0.78 | GPR35 (0.46) | EIF4ECHEK1POLQ | |
| SCHEMBL29574343 | 0.78 | GPR35 (0.46) | EIF4ECHEK1POLQ | |
| SCHEMBL25307160 | 0.75 | KDM4E (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31019034 | 0.73 | KDM4C (0.44) | SLC22A12 | |
| SCHEMBL25309052 | 0.73 | KDM4C (0.44) | SLC22A12 | |
| SCHEMBL25309450 | 0.73 | ALDH1A1 (0.38) | EIF4EGPBAR1 | |
| SCHEMBL25306780 | 0.73 | POLQ (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974043-A | Polq inhibitor compounds and uses thereof | 南京再明医药有限公司 | 2024-11-15 | — | — | CN | disclosed |